Author

Emilly Faria

Date of Award

2025

First Advisor

David Myers

Second Advisor

Sarah Snyder

Third Advisor

Amy Smith

Abstract

In this thesis, I explore the potential risks and negative impacts of thalidomide use during pregnancy. I intend to reveal the profound effects of this kind of consumption during each stage of pregnancy, explaining the changes happening to the mother and fetus at each trimester. I cover the chemistry of thalidomide, with a preliminary analysis of its molecular structure and known mechanisms of action, as well as its role in metabolic processes in animals and humans. I also discuss how the timing of exposure affects the intensity of symptoms and outcomes. Through this analysis, I proceed to the psychological effect of physical abnormalities, and the challenges individuals living with Thalidomide Embryopathy, also known as TE, face when attempting to live a normal life. Lastly, I delve into the impact on the mother, including the economic and social hardships faced by the mother and her family as a result of thalidomide.

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