Date of Submission

Spring 2024

Academic Program

Chemistry and Biochemistry

Project Advisor 1

Emily McLaughlin

Abstract/Artist's Statement

Photochemical reactions are fundamental in organic synthesis, valued for their functionality, efficiency, and reaction selectivity. Traditionally, UV light has been the preferred activation source for these reactions due to the way organic molecules absorb under it. However, visible light has recently emerged as a safer and more broadly applicable tool for photoreactions. The objective of this project is to explore the influence of different protecting groups on visible light-mediated reactions. To accomplish this, we synthesized a group of 3-acetyl indoles bearing three unique protecting groups to gauge their reactivity in visible light mediated 2+2 photocycloaddition reactions. The resulting photoproducts were reported and characterized using 1H NMR spectroscopy. This research considers the potential of visible light in photoreactions, and expands the knowledge of protecting groups in influencing reaction outcomes.

Open Access Agreement

On-Campus only

Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.

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