Photoaffinity Labeling: Marking the Receptors for Biological Molecules
(This information was taken from the Distinguished Scientist Lecture Series Program 1981-1982).
Dr. Westheimer. Morris Loeb Professor of chemistry at Harvard University, was born in Baltimore, Maryland. He received his BA degree from Dartmouth in 1932, his M.A. degree from Harvard in 1933, and his Ph.D. degree from Harvard in 1935. In 1935-36. he was a National Research Fellow at Columbia under the sponsorship of Professor L.P. Hammett. The following year he was appointed research associate at the University of Chicago, and later assistant professor. During 1944 and 1945 he was a research supervisor at the Explosive Research Laboratory of the National Defense Research Committee; as a result of this work. he was awarded the ArmyNavy Certificate of Appreciation and the Naval Ordnance Award. In 1946 he returned to Chicago as an associate professor and became full professor in 1948. He returned to Harvard as a visiting professor in 1953, was appointed professor in 1954, and served as chairman of the deportment from 1959-62. Among his numerous honors. he was a Guggenheim Fellow in 1962. and in 1974 was a Fulbright-Hayes Fellow in Yugoslavia. In 1970 he received the James Flack Norris Award in physical organic chemistry and the Willard Gibbs Medal. In 1980 he received the National Academy of Sciences Award in chemical science.
His Work: Dr. Westheimer's career has included calculations of electrostatic effects and of steric effects in organic chemistry, the determination of the mechanisms of chromic acid oxidation, enzymic and metal-ion promoted decarboxylation, biochemical oxidation-reduction reactions which require diphosphopyridine nucleotide as coenzyme, the mechanisms of the hydrolysis of phosphate esters. and photoaffinity labeling.
His Lecture: "Photoaffinity Labeling: Marking the Receptors for Biological Molecules
March 20, 1982
Westheimer, Frank H., "Photoaffinity Labeling: Marking the Receptors for Biological Molecules" (1982). DSLS 1981-1982. 8.