Gene Isolation and Manipulation: A New Window on Our Heredity


Gene Isolation and Manipulation: A New Window on Our Heredity


Paul Berg


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(This information was taken from the Distinguished Scientist Lecture Series Program 1981-1982).

Dr. Berg, Nobel laureate and Willson Professor of biochemistry at Stanford University Medical Center. was born in New York City. He is a 1948 alumnus of Pennsylvania State University and earned his Ph.D. degree in biochemistry from Western Reserve University in 1952. During the next two years he was a postdoctoral research fellow at the Institute of Cytophysiology in Copenhagen and at Washington University in St. Louis. He remained at Washington University as a scholar in cancer research and then as a faculty member until 1959, when he joined Stanford. He is a former chairman of the deportment of biochemistry at Stanford's School of Medicine. and is currently a nonresident fellow of the Salk Institute for Biological Studies. In 1980 he received the Nobel Prize in chemistry for his studies of the biochemistry of nucleic acids. particularly, recombinant DNA. He also received the 1980 Gairdner Foundation and the New York Academy of Sciences Awards in recognition of his outstanding studies of the biochemistry of nucleic acids, and the 1980 Albert Lasker Medical Award for his contributions to basic medical sciences.

His Work: At present. Dr. Berg's research is on the mechanism of gene expression in higher organisms. particularly the interplay of viral and cellular genes in regulating growth and division. Specifically, he has developed new enzymatic and physical approaches to analyzing the structure of simple viral chromosomes and thereby made possible a molecular approach to their genetics. In addition, he and his colleagues have been active in the development of recombinant DNA techniques to introduce new genetic information into mammalian cells with virus DNA vectors. These experiments are designed to explore the chemistry and biology of mammalian and human chromosomes and hopefully to provide the basic knowledge for the prevention, management and cure of hereditary diseases

His Lecture: "Gene Isolation and Manipulation: A New Window on Our Heredity"



Creation Date

May 22, 7982

Gene Isolation and Manipulation: A New Window on Our Heredity